STUDIES ON EFFECT OF ADMINISTRATION OF TETRACYCLINE ON FREE FATTY ACID METABOLISM IN ADRENALECTOMISED AND CONTROL RATS

被引：2
作者：
MUKHERJEE, D
GHOSH, H
MUKHERJEE, S
机构：
[1] Standard Pharmaceuticals Limited
[2] Department of Applied Chemistry, University of Calcutta
来源：
JOURNAL OF ANTIBIOTICS | 1969年 / 22卷 / 10期
关键词：
D O I：
10.7164/antibiotics.22.480
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Administration of therapeutic doses of tetracycline hydrochloride to rats results in increased accumulation of triglyceride in the liver. Phospholipid concentration of the liver is decreased under such conditions, whereas both free and esterified cholesterol levels remain unaffected. Elevation of the free fatty acid level of plasma, induced by tetracycline administration, is due to increased mobilisation of free fatty acids from adipose tissue. The antibiotic was found to be ineffective in stimulating the mobilisation of free fatty acids from the epididymal fatpad of adrenalectomised rats. © 1969, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.
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页码：480 / +
页数：1
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