SYNTHESIS AND STEREOCHEMISTRY OF SOME NEW CHIRAL BROMINATED 1,3-DIOXANES

被引：20

作者：

GROSU, I

PLE, G

MAGER, S

机构：

[1] UNIV ROUEN,FAC SCI,F-76821 MONT ST AIGNAN,FRANCE

[2] IRCOF,CNRS,LAB DO464,F-76821 MONT ST AIGNAN,FRANCE

来源：

TETRAHEDRON | 1995年 / 51卷 / 09期

关键词：

D O I：

10.1016/0040-4020(94)01112-D

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The stereochemistry of some new 1,3-dioxanes with brominated chiral groups located in the (a)ketalic part of the heterocycle, obtained by a regioselective radicalic bromination reaction, nas investigated by NMR methods. The experiments demonstrated the fixed or flipping structures of the compounds. The influence of the chiral carbon atoms was analyzed by means of the diastereotopicity of protons and carbon atoms. In the case of polychiral compounds, the diastereoselectivity of the bromi-nation reaction was studied.

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页码：2659 / 2672

页数：14

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