FACILE ENZYMATIC PREPARATION OF ENANTIOMERIC BETA-LACTAMS

被引：0
作者：
NAGAI, H
SHIOZAWA, T
ACHIWA, K
TERAO, Y
机构：
[1] UNIV SHIZUOKA, GRAD SCH NUTR & ENVIRONM SCI, DIV ENVIRONM HLTH SCI, 51-2 YADA, OYA, SHIZUOKA 422, JAPAN
[2] UNIV SHIZUOKA, SCH PHARMACEUT SCI, OYA, SHIZUOKA 422, JAPAN
来源：
CHEMICAL & PHARMACEUTICAL BULLETIN | 1992年 / 40卷 / 08期
关键词：
BETA-LACTAM; LIPASE; RESOLUTION; HYDROLYSIS; ESTERIFICATION;
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Optically active beta-lactams were obtained conveniently by lipase-catalyzed enantioselective hydrolysis of 1-acyloxymethyl-2-azetidinones and esterification of 1-hydroxymethyl-3,3-dimethyl-2-azetidinone with vinyl acetate in organic solvent.
引用
收藏
页码：2227 / 2229
页数：3
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