4-HYDROXY-3-NITROSOBENZAMIDE AND ITS FERROUS CHELATE FROM STREPTOMYCES-MURAYAMAENSIS

被引：20

作者：

CONE, MC ^{[1
]}

MELVILLE, CR ^{[1
]}

CARNEY, JR ^{[1
]}

GORE, MP ^{[1
]}

GOULD, SJ ^{[1
]}

机构：

[1] OREGON STATE UNIV,DEPT CHEM,CORVALLIS,OR 97331

来源：

TETRAHEDRON | 1995年 / 51卷 / 11期

关键词：

D O I：

10.1016/0040-4020(95)00071-F

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two new colored metabolites of Streptomyces murayamaensis have been isolated and characterized as 4-hydroxy-3-nitrosobenzamide and its ferrous chelate. These structures have been confirmed by synthesis via a modified Baudisch reaction. A sample of 3-amino-4-hydroxy[2-H-2]benzoic acid was fed to S. murayamaensis, affording a sample of the 4-hydroxy-3-nitrosobenzamide ferrous chelate deuterated at C-2 (28.5% enrichment, 3.2% incorporation).

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页码：3095 / 3102

页数：8

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