URINARY-BLADDER CANCER FOLLOWING CYCLOPHOSPHAMIDE THERAPY FOR HODGKINS-DISEASE

被引:11
作者
PATHAK, AB [1 ]
ADVANI, SH [1 ]
GOPAL, R [1 ]
NADKARNI, KS [1 ]
SAIKIA, TK [1 ]
机构
[1] TATA MEM HOSP,DEPT MED ONCOL,BOMBAY 400012,INDIA
关键词
BLADDER CANCER; CYCLOPHOSPHAMIDE; LYMPHOMA; MESNA;
D O I
10.3109/10428199209051035
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Urinary bladder cancers following prolonged cyclophosphamide therapy are being increasingly reported. We report a case of transitional cell carcinoma of the urinary bladder occurring 12 years after pulse intravenous therapy with cyclophosphamide for Hodgkin's disease. The mechanism of bladder carcinogenesis and the possible role of the uroprotector MESNA in preventing cyclophosphamide induced bladder cancer are discussed.
引用
收藏
页码:503 / 504
页数:2
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