Optimal left ventricular lead placement for cardiac resynchronization therapy in postmyocardial infarction patients

被引：0

作者：

Muto, Carmine ^{[1
]}

Solimene, Francesco ^{[2
]}

Russo, Vincenzo ^{[3
]}

Nigro, Gerardo ^{[3
]}

Rago, Anna ^{[3
]}

Chianese, Raffaele ^{[1
]}

Chiariello, Paola ^{[4
]}

Ciardiello, Carmine ^{[5
]}

Caliendo, Luigi ^{[1
]}

机构：

[1] Osped Santa Maria della Pieta, Cardiol, Naples, Italy

[2] Casa Cura Montevergine, Elttrostimolaz & Elettrofisiol, Avellino, Italy

[3] Univ Naples 2, Monaldi Hosp, Chair Cardiol, Cardiol, Naples, Italy

[4] Osped Santa Maria dellOlmo, Cardiol, Salerno, Italy

[5] HT MED, Clin Affairs, Naples, Italy

来源：

FUTURE CARDIOLOGY | 2018年 / 14卷 / 03期

关键词：

cardiac resynchronization therapy; CRT responders; LV remodeling; ventricular mechanical activation;

D O I：

10.2217/fca-2017-0046

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Aim: To evaluate at a 12-month follow-up, the clinical and echocardiographic outcomes in postmyocardial infarction (MI) heart failure patients who underwent cardiac resynchronization therapy (CRT) device implantation. Materials & methods: A total of 100 patients received a CRT device, and the study population was divided into three groups, according to the site of MI and left ventricular (LV) lead placed downstream of the ischemic area, as evaluated by echocardiography. Results: At the end of the 12-month follow-up, we reported a general improvement of LV ejection fraction from 28 +/- 7% to 35 +/- 9% (p < 0.001) and a significant reverse remodeling: LV end-systolic volume changed from 147 +/- 54 to 125 +/- 63 (p = 0.001) with a 53% of echocardiographic responders. We also observed 67% of CRT responders in the group with optimal LV lead placement compared with 38% in the remaining population (p = 0.01). Conclusion: The optimal positioning of LV lead is a feasible method to improve the percentage of CRT responders in post-MI heart failure patients.

引用

页码：215 / 224

页数：10

共 42 条

[1] Cardiac resynchronization in chronic heart failure [J].

Abraham, WT ;

Fisher, WG ;

Smith, AL ;

Delurgio, DB ;

Leon, AR ;

Loh, E ;

Kocovic, DZ ;

Packer, M ;

Clavell, AL ;

Hayes, DL ;

Ellestad, M ;

Messenger, J ;

Trupp, RJ ;

Underwood, J ;

Pickering, F ;

Truex, C ;

McAtee, P .

NEW ENGLAND JOURNAL OF MEDICINE, 2002, 346 (24) :1845-1853

[2] Scar burden by myocardial perfusion imaging predicts echocardiographic response to cardiac resynchronization therapy in ischemic cardiomyopathy [J].

Adelstein, Evan C. ;

Saba, Samir .

AMERICAN HEART JOURNAL, 2007, 153 (01) :105-112

[3] Doppler myocardial imaging in patients with heart failure receiving biventricular pacing treatment [J].

Ansalone, G ;

Giannantoni, P ;

Ricci, R ;

Trambaiolo, P ;

Laurenti, A ;

Fedele, F ;

Santini, M .

AMERICAN HEART JOURNAL, 2001, 142 (05) :881-896

[4] End-diastolic wall thickness as a predictor of reverse remodelling after cardiac resynchronization therapy: A two-dimensional echocardiographic study [J].

Ascione, Luigi ;

Muto, Carmine ;

Iengo, Raffaele ;

Celentano, Eduardo ;

Accadia, Maria ;

Rumolo, Salvatore ;

D'Andrea, Antonello ;

Carreras, Giovanni ;

Canciello, Michelangelo ;

Tuccillo, Bernardino .

JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY, 2008, 21 (09) :1055-1061

[5] Long-term clinical effect of hemodynamically optimized cardiac resynchronization therapy in patients with heart failure and ventricular conduction delay [J].

Auricchio, A ;

Stellbrink, C ;

Sack, S ;

Block, M ;

Vogt, J ;

Bakker, P ;

Huth, C ;

Schöndube, F ;

Wolfhard, U ;

Böcker, D ;

Krahnefeld, O ;

Kirkels, H .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2002, 39 (12) :2026-2033

[6] Relation of optimal lead positioning as defined by three-dimensional Echocardiography to long-term benefit of cardiac resynchronization [J].

Becker, Michael ;

Hoffmann, Rainer ;

Schmitz, Fabian ;

Hundemer, Anne ;

Kuehl, Harald ;

Schauerte, Patrick ;

Kelm, Malte ;

Franke, Andreas .

AMERICAN JOURNAL OF CARDIOLOGY, 2007, 100 (11) :1671-1676

[7] Impact of left ventricular lead position on the efficacy of cardiac resynchronisation therapy: a two-dimensional strain echocardiography study [J].

Becker, Michael ;

Franke, Andreas ;

Breithardt, Ole A. ;

Ocklenburg, Christina ;

Kaminski, Theresa ;

Kramann, Rafael ;

Knackstedt, Christian ;

Stellbrink, Christoph ;

Hanrath, Peter ;

Schauerte, Patrick ;

Hoffmann, Rainer .

HEART, 2007, 93 (10) :1197-1203

[8] Cardiac resynchronisation therapy for heart failure [J].

Behan, M. W. H. ;

Rinaldi, C. A. .

INTERNATIONAL JOURNAL OF CLINICAL PRACTICE, 2006, 60 (09) :1107-1114

[9] Impact of Mechanical Activation, Scar, and Electrical Timing on Cardiac Resynchronization Therapy Response and Clinical Outcomes [J].

Bilchick, Kenneth C. ;

Kuruvilla, Sujith ;

Hamirani, Yasmin S. ;

Ramachandran, Raghav ;

Clarke, Samantha A. ;

Parker, Katherine M. ;

Stukenborg, George J. ;

Mason, Pamela ;

Ferguson, John D. ;

Moorman, J. Randall ;

Malhotra, Rohit ;

Mangrum, J. Michael ;

Darby, Andrew E. ;

DiMarco, John ;

Holmes, Jeffrey W. ;

Salerno, Michael ;

Kramer, Christopher M. ;

Epstein, Frederick H. .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2014, 63 (16) :1657-1666

[10] Effect of posterolateral scar tissue on clinical and echocardiographic improvement after cardiac resynchronization therapy [J].

Bleeker, GB ;

Kaandorp, TAM ;

Lamb, HJ ;

Boersma, E ;

Steendijk, P ;

de Roos, A ;

van der Wall, EE ;

Schalij, MJ ;

Bax, JJ .

CIRCULATION, 2006, 113 (07) :969-976

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