FROM INITIATION TO ELONGATION - COMPARISON OF TRANSCRIPTION BY PROKARYOTIC AND EUKARYOTIC RNA-POLYMERASES

被引：32

作者：

EICK, D ^{[1
]}

WEDEL, A ^{[1
]}

HEUMANN, H ^{[1
]}

机构：

[1] MAX PLANCK INST BIOCHEM,D-82152 MARTINSRIED,GERMANY

来源：

TRENDS IN GENETICS | 1994年 / 10卷 / 08期

关键词：

D O I：

10.1016/0168-9525(90)90013-V

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Multisubunit RNA polymerases in prokaryotes and eukaryotes share an evolutionarily, conserved!en core. Here, we compare the processes of promoter recognition, transcription initiation and transcript elongation by human RNA polymerase II and by the RNA polymerase of the eubacterium Escherichia coli. Although these two polymerases have diverged widely in structure, important functions have been conserved suggesting that the basic mechanisms of RNA transcription are similar in eukaryotes and prokaryotes.

引用

页码：292 / 296

页数：5

共 45 条

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