FROM INITIATION TO ELONGATION - COMPARISON OF TRANSCRIPTION BY PROKARYOTIC AND EUKARYOTIC RNA-POLYMERASES

被引：32

作者：

EICK, D ^{[1
]}

WEDEL, A ^{[1
]}

HEUMANN, H ^{[1
]}

机构：

[1] MAX PLANCK INST BIOCHEM,D-82152 MARTINSRIED,GERMANY

来源：

TRENDS IN GENETICS | 1994年 / 10卷 / 08期

关键词：

D O I：

10.1016/0168-9525(90)90013-V

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Multisubunit RNA polymerases in prokaryotes and eukaryotes share an evolutionarily, conserved!en core. Here, we compare the processes of promoter recognition, transcription initiation and transcript elongation by human RNA polymerase II and by the RNA polymerase of the eubacterium Escherichia coli. Although these two polymerases have diverged widely in structure, important functions have been conserved suggesting that the basic mechanisms of RNA transcription are similar in eukaryotes and prokaryotes.

引用

收藏

页码：292 / 296

页数：5

相关论文

共 45 条

[11] CLONING OF A HUMAN GENE ENCODING THE GENERAL TRANSCRIPTION INITIATION FACTOR-IIB [J].

HA, I ;

LANE, WS ;

REINBERG, D .

NATURE, 1991, 352 (6337) :689-695

[12] STRUCTURE AND FUNCTION OF BACTERIAL SIGMA FACTORS [J].

HELMANN, JD ;

CHAMBERLIN, MJ .

ANNUAL REVIEW OF BIOCHEMISTRY, 1988, 57 :839-872

[13] SPATIAL ARRANGEMENT OF DNA-DEPENDENT RNA-POLYMERASE OF ESCHERICHIA-COLI AND DNA IN THE SPECIFIC COMPLEX - A NEUTRON SMALL-ANGLE SCATTERING STUDY [J].

HEUMANN, H ;

LEDERER, H ;

BAER, G ;

MAY, RP ;

KJEMS, JK ;

CRESPI, HL .

JOURNAL OF MOLECULAR BIOLOGY, 1988, 201 (01) :115-125

[14] CLONING AND STRUCTURE OF A YEAST GENE ENCODING A GENERAL TRANSCRIPTION INITIATION-FACTOR TFIID THAT BINDS TO THE TATA BOX [J].

HORIKOSHI, M ;

WANG, CK ;

FUJII, H ;

CROMLISH, JA ;

WEIL, PA ;

ROEDER, RG .

NATURE, 1989, 341 (6240) :299-303

[15] THE RNA POLYMERASE-II TERNARY COMPLEX CLEAVES THE NASCENT TRANSCRIPT IN A 3'-]5' DIRECTION IN THE PRESENCE OF ELONGATION FACTOR-SII [J].

IZBAN, MG ;

LUSE, DS .

GENES & DEVELOPMENT, 1992, 6 (07) :1342-1356

[16] STRUCTURE OF TRANSCRIPTION ELONGATION COMPLEXES INVIVO [J].

KAINZ, M ;

ROBERTS, J .

SCIENCE, 1992, 255 (5046) :838-841

[17] RNA-POLYMERASE MARCHING BACKWARD [J].

KASSAVETIS, GA ;

GEIDUSCHEK, EP .

SCIENCE, 1993, 259 (5097) :944-945

[18] THE BLOCK TO TRANSCRIPTIONAL ELONGATION WITHIN THE HUMAN C-MYC GENE IS DETERMINED IN THE PROMOTER - PROXIMAL REGION [J].

KRUMM, A ;

MEULIA, T ;

BRUNVAND, M ;

GROUDINE, M .

GENES & DEVELOPMENT, 1992, 6 (11) :2201-2213

[19] STRUCTURAL-ANALYSIS OF TERNARY COMPLEXES OF ESCHERICHIA-COLI RNA-POLYMERASE - INDIVIDUAL COMPLEXES HALTED ALONG DIFFERENT TRANSCRIPTION UNITS HAVE DISTINCT AND UNEXPECTED BIOCHEMICAL-PROPERTIES [J].

KRUMMEL, B ;

CHAMBERLIN, MJ .

JOURNAL OF MOLECULAR BIOLOGY, 1992, 225 (02) :221-237

[20] STRUCTURAL-ANALYSIS OF TERNARY COMPLEXES OF ESCHERICHIA-COLI RNA-POLYMERASE - DEOXYRIBONUCLEASE-I FOOTPRINTING OF DEFINED COMPLEXES [J].

KRUMMEL, B ;

CHAMBERLIN, MJ .

JOURNAL OF MOLECULAR BIOLOGY, 1992, 225 (02) :239-250

← 1 2 3 4 5 →