FROM INITIATION TO ELONGATION - COMPARISON OF TRANSCRIPTION BY PROKARYOTIC AND EUKARYOTIC RNA-POLYMERASES

被引：32
作者：
EICK, D [1 ]
WEDEL, A [1 ]
HEUMANN, H [1 ]
机构：
[1] MAX PLANCK INST BIOCHEM,D-82152 MARTINSRIED,GERMANY
来源：
TRENDS IN GENETICS | 1994年 / 10卷 / 08期
关键词：
D O I：
10.1016/0168-9525(90)90013-V
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Multisubunit RNA polymerases in prokaryotes and eukaryotes share an evolutionarily, conserved!en core. Here, we compare the processes of promoter recognition, transcription initiation and transcript elongation by human RNA polymerase II and by the RNA polymerase of the eubacterium Escherichia coli. Although these two polymerases have diverged widely in structure, important functions have been conserved suggesting that the basic mechanisms of RNA transcription are similar in eukaryotes and prokaryotes.
引用
收藏
页码：292 / 296
页数：5
相关论文
共 45 条
[1]   GREA PROTEIN - A TRANSCRIPTION ELONGATION-FACTOR FROM ESCHERICHIA-COLI [J].
BORUKHOV, S ;
POLYAKOV, A ;
NIKIFOROV, V ;
GOLDFARB, A .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (19) :8899-8902
[2]   TRANSCRIPT CLEAVAGE FACTORS FROM ESCHERICHIA-COLI [J].
BORUKHOV, S ;
SAGITOV, V ;
GOLDFARB, A .
CELL, 1993, 72 (03) :459-466
[3]   KINETICS OF OPEN COMPLEX-FORMATION BETWEEN ESCHERICHIA-COLI RNA-POLYMERASE AND THE LAC UV5 PROMOTER - EVIDENCE FOR A SEQUENTIAL MECHANISM INVOLVING 3 STEPS [J].
BUC, H ;
MCCLURE, WR .
BIOCHEMISTRY, 1985, 24 (11) :2712-2723
[4]   5 INTERMEDIATE COMPLEXES IN TRANSCRIPTION INITIATION BY RNA POLYMERASE-II [J].
BURATOWSKI, S ;
HAHN, S ;
GUARENTE, L ;
SHARP, PA .
CELL, 1989, 56 (04) :549-561
[5]  
CONAWAY RC, 1993, ANNU REV BIOCHEM, V62, P161
[6]   3-DIMENSIONAL STRUCTURE OF ESCHERICHIA-COLI RNA-POLYMERASE HOLOENZYME DETERMINED BY ELECTRON CRYSTALLOGRAPHY [J].
DARST, SA ;
KUBALEK, EW ;
KORNBERG, RD .
NATURE, 1989, 340 (6236) :730-732
[7]  
DAS A, 1993, ANNU REV BIOCHEM, V62, P893
[8]   THE SMALL SUBUNIT OF TRANSCRIPTION FACTOR-IIF RECRUITS RNA POLYMERASE-II INTO THE PREINITIATION COMPLEX [J].
FLORES, O ;
LU, H ;
KILLEEN, M ;
GREENBLATT, J ;
BURTON, ZF ;
REINBERG, D .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (22) :9999-10003
[9]   PROMOTER MELTING AND TFIID COMPLEXES ON DROSOPHILA GENES INVIVO [J].
GIARDINA, C ;
PEREZRIBA, M ;
LIS, JT .
GENES & DEVELOPMENT, 1992, 6 (11) :2190-2200
[10]   TRANSCRIPTIONAL ANTITERMINATION [J].
GREENBLATT, J ;
NODWELL, JR ;
MASON, SW .
NATURE, 1993, 364 (6436) :401-406
12345