A Quantitative Signature of Self-Control Repair: Rate-Dependent Effects of Successful Addiction Treatment
被引:24
作者:
Bickel, Warren K.
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机构:
Virginia Tech Caril Res Inst, Addict Recovery Res Ctr, 2 Riverside Circle, Roanoke, VA 24016 USAVirginia Tech Caril Res Inst, Addict Recovery Res Ctr, 2 Riverside Circle, Roanoke, VA 24016 USA
Bickel, Warren K.
[1
]
Landes, Reid D.
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机构:
Univ Arkansas Med Sci, Dept Biostat, Little Rock, AR 72205 USAVirginia Tech Caril Res Inst, Addict Recovery Res Ctr, 2 Riverside Circle, Roanoke, VA 24016 USA
Landes, Reid D.
[2
]
Kurth-Nelson, Zeb
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机构:
UCL, Wellcome Trust Ctr Neuroimaging, Inst Neurol, London, EnglandVirginia Tech Caril Res Inst, Addict Recovery Res Ctr, 2 Riverside Circle, Roanoke, VA 24016 USA
Kurth-Nelson, Zeb
[3
]
Redish, A. David
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Univ Minnesota, Dept Neurosci, Minneapolis, MN 55455 USAVirginia Tech Caril Res Inst, Addict Recovery Res Ctr, 2 Riverside Circle, Roanoke, VA 24016 USA
Redish, A. David
[4
]
机构:
[1] Virginia Tech Caril Res Inst, Addict Recovery Res Ctr, 2 Riverside Circle, Roanoke, VA 24016 USA
[2] Univ Arkansas Med Sci, Dept Biostat, Little Rock, AR 72205 USA
[3] UCL, Wellcome Trust Ctr Neuroimaging, Inst Neurol, London, England
[4] Univ Minnesota, Dept Neurosci, Minneapolis, MN 55455 USA
Excessive temporal discounting undergirds addiction, and the quantitative relationships of changes in discounting have yet to be investigated. The quantitative relationship between pre-and posttreatment discount rates was examined using data from five of our studies with diverse interventions across different groups of substance users. Discounting and treatment-outcome drug-use data from 222 drug-dependent individuals were analyzed. The primary measures were discounting of delayed reinforcers and objective measures of drug use. Results revealed that change in discounting was inversely related to baseline rates of discounting, such that participants with low discount rates showed little change in discounting with treatment, whereas participants with high discount rates showed large reductions in discounting. As importantly, those treatments that produced the largest gains in drug abstinence had the largest effects on discount rates. Temporal discounting changes with the specific quantitative signature of rate dependence, and more efficacious treatments remediate high discounting rates.
机构:
Johns Hopkins Univ, Sch Med, Behav Pharmacol Res Unit, Baltimore, MD 21224 USAJohns Hopkins Univ, Sch Med, Behav Pharmacol Res Unit, Baltimore, MD 21224 USA
Johnson, Matthew W.
;
Bickel, Warren K.
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Univ Arkansas Med Sci, Addict Res Ctr, Inst Psychiat Res, Little Rock, AR 72205 USAJohns Hopkins Univ, Sch Med, Behav Pharmacol Res Unit, Baltimore, MD 21224 USA
机构:
Johns Hopkins Univ, Sch Med, Behav Pharmacol Res Unit, Baltimore, MD 21224 USAJohns Hopkins Univ, Sch Med, Behav Pharmacol Res Unit, Baltimore, MD 21224 USA
Johnson, Matthew W.
;
Bickel, Warren K.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Arkansas Med Sci, Addict Res Ctr, Inst Psychiat Res, Little Rock, AR 72205 USAJohns Hopkins Univ, Sch Med, Behav Pharmacol Res Unit, Baltimore, MD 21224 USA