Impact of mycotoxin on immune response and consequences for pig health

被引：139
作者：
Pierron, Alix [1 ,2 ,3 ]
Alassane-Kpembi, Imourana [1 ,2 ]
Oswald, Isabelle P. [1 ,2 ]
机构：
[1] INRA, UMR 1331, ToxAlim Res Ctr Food Toxicol, BP93173, F-31027 Toulouse 03, France
[2] Univ Toulouse, INP, UMR 1331, F-31027 Toulouse 03, France
[3] BIOMIN Res Ctr, A-3430 Tulin, Austria
来源：
ANIMAL NUTRITION | 2016年 / 2卷 / 02期
关键词：
Pig; Mycotoxins; Feed contamination; Susceptibility to disease; Immunity; Vaccine efficacy;
D O I：
10.1016/j.aninu.2016.03.001
中图分类号：
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号：
0905 ;
摘要：
Mycotoxins are fungal secondary metabolites detected in many agricultural commodities, especially cereals. Due to their high consumption of cereals, pigs are exposed to these toxins. In the European Union, regulations and/or recommendations exist in pig feed for aflatoxins, ochratoxin A, fumonisins, zearalenone, and trichothecenes, deoxynivalenol and T-2 toxin. These mycotoxins have different toxic effects, but they all target the immune system. They have immunostimulatory or immunosuppressive effects depending on the toxin, the concentration and the parameter investigated. The immune system is primarily responsible for defense against invading organisms. The consequences of the ingestion of mycotoxin-contaminated feed are an increased susceptibility to infectious diseases, a reactivation of chronic infection and a decreased vaccine efficacy. In this review we summarized the data available on the effect of mycotoxins on the immune system and the consequences for pig health. (C) 2016, Chinese Association of Animal Science and Veterinary Medicine. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd.
引用
收藏
页码：63 / 68
页数：6
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