PATHOGENESIS OF OXALATE UROLITHIASIS - LESSONS FROM EXPERIMENTAL STUDIES WITH RATS

被引：43

作者：

KHAN, SR ^{[1
]}

机构：

[1] UNIV FLORIDA,COLL MED,DEPT PATHOL,GAINESVILLE,FL 32611

来源：

AMERICAN JOURNAL OF KIDNEY DISEASES | 1991年 / 17卷 / 04期

关键词：

UROLITHIASIS; KIDNEY STONE; CRYSTAL RETENTION; HYPEROXALURIA; NEPHROLITHIASIS;

D O I：

10.1016/S0272-6386(12)80631-7

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Calcium oxalate (CaOx) urolithiasis in rats is induced by producing hyperoxaluria. Depending on the degree and length of hyperoxaluria, CaOx crystals may either form in the nephron or the bladder and may or may not be retained in the kidneys. Crystals may nucleate in one part of the nephron and be retained in another part. Papillary collecting duct tubular epithelium and its basement membrane appear to be involved in crystal retention in the kidneys. © 1991, National Kidney Foundation, Inc.. All rights reserved.

引用

页码：398 / 401

页数：4

共 18 条

[1]

FINLAYSON B, 1978, KIDNEY INT, V13, P334

[2]

GILL WB, 1979, INVEST UROL, V17, P257

[3]

GREGORY JG, 1984, URINAR STONE

[4] CELL INJURY ASSOCIATED CALCIUM-OXALATE CRYSTALLURIA [J].