PATIENTS WITH EROSIVE LICHEN-PLANUS MAY HAVE ANTIBODIES DIRECTED TO A NUCLEAR ANTIGEN OF EPITHELIAL-CELLS - A STUDY ON THE ANTIGEN NATURE

被引：39

作者：

PARODI, A ^{[1
]}

CARDO, PP ^{[1
]}

机构：

[1] UNIV GENOA,LEPROSY & TROP DERMATOL RES CTR,IMMUNOPATHOL LAB,I-16132 GENOA,ITALY

来源：

JOURNAL OF INVESTIGATIVE DERMATOLOGY | 1990年 / 94卷 / 05期

关键词：

D O I：

10.1111/1523-1747.ep12876269

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Two patients with erosive lichen planus and latent HBV infection who had circulating antibodies directed to nuclei of epithelial cells are described. The nature of such antigen has been investigated by indirect immunofluorescence, double immunodiffusion, counterimmunoelectrophoresis, enzyme-linked immunosorbent assay, enzyme treatments, and immunoblotting. The antigen cannot be identified as RNP, histone, soluble nuclear protein, nDNA, or ssDNA. It may be a DNA protein complex and preliminary immunoblotting data support the thesis that it may be a multimolecular complex. © 1990.

引用

页码：689 / 693

页数：5

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