WHICH WAY FOR DRUG-MEDIATED IMMUNOSUPPRESSION

被引：36
作者：
SHARMA, VK
LI, BG
KHANNA, A
SEHAJPAL, PK
SUTHANTHIRAN, M
机构：
[1] The New York Hospital-Cornell Medical Center, NY
来源：
CURRENT OPINION IN IMMUNOLOGY | 1994年 / 6卷 / 05期
关键词：
D O I：
10.1016/0952-7915(94)90085-X
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The basic immunosuppressive protocol involves the use of multiple drugs, each directed at a discrete site in the T-cell activation cascade. The prevailing paradigm regarding the mechanisms of action of immunosuppressants is that they function to prevent allograft rejection by preventing cell activation, proliferation and/or cytokine production. A new hypothesis is that some of the immunosuppressants might function by stimulating the expression of immunosuppressive molecules and/or cells.
引用
收藏
页码：784 / 790
页数：7
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