THE ALKALOIDS OF MARGARITARIA-INDICA .2. THE STRUCTURES OF 4-EPIPHYLLANTHINE, MARGARITARINE AND THE STRUCTURAL REVISION OF SECURINOL-A

被引：39

作者：

ARBAIN, D ^{[1
]}

BIRKBECK, AA ^{[1
]}

BYRNE, LT ^{[1
]}

SARGENT, MV ^{[1
]}

SKELTON, BW ^{[1
]}

WHITE, AH ^{[1
]}

机构：

[1] UNIV WESTERN AUSTRALIA,DEPT CHEM,NEDLANDS,WA 6009,AUSTRALIA

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1991年 / 08期

关键词：

D O I：

10.1039/p19910001863

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Extraction of the bark of Margaritaria indica has yielded the new alkaloids (4-alpha)-4-methoxysecurinan-11-one 3 and 3-{N-[(2-alpha, 15-alpha)-14, 15-dihydro-11-oxosecurinan-15-yl]-2-aminoethyl}-1H-indole 10. Their structures followed from their spectroscopic properties. High field NMR spectra for the known Securinega alkaloids (4-beta)-4-methoxysecurinan-11-one 2 and (2-alpha,4-alpha)-4-methoxysecurinan-11-one 5 were recorded and interpreted. The structure of the known alkaloid securinol A is revised to 17 as a result of an X-ray crystal structure determination of its hydrobromide.

引用

页码：1863 / 1869

页数：7

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