POTENTIAL ANTI-TUMOR AGENTS .10. CYTOTOXIC NORDITERPENE DILACTONES OF PODOCARPUS-MILANJIANUS AND PODOCARPUS-SELLOWII

被引：29
作者：
HEMBREE, JA
CHANG, CJ
MCLAUGHLIN, JL
CASSADY, JM
WATTS, DJ
WENKERT, E
FONSECA, SF
CAMPELLO, JDP
机构：
[1] PURDUE UNIV,SCH PHARM & PHARMACAL SCI,DEPT MED CHEM & PHARMACOGNOSY,W LAFAYETTE,IN 47907
[2] INDIANA UNIV,DEPT CHEM,BLOOMINGTON,IN 47401
[3] UNIV ESTADUAL CAMPINAS,INST QUIM,CAMPINAS 13100,SP,BRAZIL
来源：
PHYTOCHEMISTRY | 1979年 / 18卷 / 10期
关键词：
9KB cytotoxicity; bark; nagilactone F; nagilactone G; norditerpene dilactones; Podocarpaceae; Podocarpus milanjianus and Podocarpus sellowii; structural analysis;
D O I：
10.1016/0031-9422(79)80185-5
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The cytotoxic norditerpene dilactones nagilactone F and its new congener nagilactone G have been isolated from the bark constituents of Podocarpus milanjianus and Podocarpus sellowii. The diterpenes totarol, 19-oxototarol and macrophyllic acid were also isolated. © 1979.
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收藏
页码：1691 / 1694
页数：4
相关论文
共 24 条
[1]   THE TAXONOMIC DISTRIBUTION OF SOME DITERPENE HYDROCARBONS [J].
APLIN, RT ;
CAMBIE, RC ;
RUTLEDGE, PS .
PHYTOCHEMISTRY, 1963, 2 (03) :205-214
[2]   CHEMISTRY OF PODOCARPACEAE .7. PODOTOTARIN AND CONSTITUENTS OF HEARTWOOD OF PODOCARPUS HALLII KIRK [J].
CAMBIE, RC ;
SIMPSON, WRJ ;
COLEBROOK, LD .
TETRAHEDRON, 1963, 19 (01) :209-&
[3]   CHEMISTRY OF NATURAL ORDER CUPRESSALES .45. STRUCTURE AND CONFIGURATION OF TOTAROL AND TOTAROLONE [J].
CHOW, YL ;
ERDTMAN, H .
ACTA CHEMICA SCANDINAVICA, 1962, 16 (06) :1305-&
[4]  
ENZEL CR, 1966, ARK KEMI, V26, P425
[5]   PLANT-GROWTH INHIBITORY LACTONES FROM PODOCARPUS-NERIIFOLIUS - STRUCTURE OF PODOLACTONE-E [J].
GALBRAIT.MN ;
SASSE, JM ;
HORN, DHS .
EXPERIENTIA, 1972, 28 (03) :253-&
[6]  
GALBRAITH MN, 1970, CHEM COMMUN, P170
[7]  
GERAN RI, 1972, CANC CHEMOTHER REP, V3, P1
[8]  
HAYASHI Y, 1977, TETRAHEDRON LETT, P4215
[9]   STRUCTURES OF NAGILACTONE E AND F, AND BIOLOGICAL-ACTIVITY OF NAGILACTONES AS PLANT-GROWTH REGULATOR [J].
HAYASHI, Y ;
YAMAMOTO, R ;
WATANABE, Y ;
SAKAN, T ;
YOKOI, J ;
MASUDA, Y .
CHEMISTRY LETTERS, 1972, (09) :759-+
[10]  
HAYASHI Y, 1977, TETRAHEDRON LETT, P3637
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