REPEATED ANTIGENIC CHALLENGE INDUCES EARTHWORM CELOMOCYTE PROLIFERATION

被引：19

作者：

BILEJ, M ^{[1
]}

SIMA, P ^{[1
]}

SLIPKA, J ^{[1
]}

机构：

[1] CHARLES UNIV, FAC MED, CS-30599 PLZEN, CZECHOSLOVAKIA

来源：

IMMUNOLOGY LETTERS | 1992年 / 32卷 / 02期

关键词：

EISENIA-FOETIDA; CELOMOCYTE; PROLIFERATION; ANTIGENIC STIMULATION;

D O I：

10.1016/0165-2478(92)90112-2

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Annelids are able to protect themselves against foreign materials by natural and acquired cellular immunity. The aim of this study was to characterize the kinetic of antigen induced proliferation of earthworm coelomocytes. The proliferative activity of free coelomocytes of Eisenia foetida decreased after antigenic stimulation and increased after a second contact with the same antigen. Precursor cells in the mesenchymal lining of the coelomic cavity responded to stimulation immediately. These results indicate that for a successful triggering of the proliferative response of the free coelomocytes repeated contact with stimulating agents is needed.

引用

页码：181 / 184

页数：4

共 21 条

[1]

BAILEY S, 1971, IMMUNOLOGY, V21, P81

[2] INVITRO ANTIGEN-BINDING PROPERTIES OF CELOMOCYTES OF EISENIA-FOETIDA (ANNELIDA) [J].