8 BASE CHANGES ARE SUFFICIENT TO CONVERT A LEUCINE-INSERTING TRANSFER-RNA INTO A SERINE-INSERTING TRANSFER-RNA

被引：95
作者：
NORMANLY, J [1 ]
OLLICK, T [1 ]
ABELSON, J [1 ]
机构：
[1] CALTECH, DIV BIOL, PASADENA, CA 91125 USA
来源：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1992年 / 89卷 / 12期
关键词：
D O I：
10.1073/pnas.89.12.5680
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Each aminoacyl-tRNA synthetase must functionally distinguish its cognate tRNAs from all others. We have determined the minimum number of changes required to transform a leucine amber suppressor tRNA to serine identity. Eight changes are required. These are located in the acceptor stem and in the D stem.
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页码：5680 / 5684
页数：5
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