ORIGIN OF LUTEINIZING-HORMONE-RELEASING HORMONE (LHRH) NEURONS IN THE CHICK-EMBRYO - EFFECT OF THE OLFACTORY PLACODE ABLATION

被引：82
作者：
AKUTSU, S
TAKADA, M
OHKIHAMAZAKI, H
MURAKAMI, S
ARAI, Y
机构：
[1] JUNTENDO UNIV,SCH MED,DEPT ANAT,TOKYO 113,JAPAN
[2] JUNTENDO UNIV,SCH MED,DEPT OBSTET & GYNECOL,TOKYO 113,JAPAN
[3] WASEDA UNIV,SCH HUMAN SCI,DEPT BASIC HUMAN SCI,TOKYO 160,JAPAN
来源：
NEUROSCIENCE LETTERS | 1992年 / 142卷 / 02期
关键词：
LUTEINIZING HORMONE-RELEASING HORMONE NEURON; OLFACTORY PLACODAL ORIGIN; CELL MIGRATION; PLACODECTOMY; CHICK EMBRYO;
D O I：
10.1016/0304-3940(92)90382-H
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
A unilateral olfactory placodectomy resulted in the absence of luteinizing hormone-releasing hormone-immunoreactive (LHRH-ir) cells in the olfactory-forebrain axis of the operated side, whereas the development of the LHRH neuronal system was not disturbed on the unoperated side. In the embryos in which a fragment of the medial olfactory epithelium was spared the damage, a small number of LHRH-ir cells were detected in the nasal region of the operated side, where the lack of the central projection of the olfactory nerve caused stagnation of LHRH-ir cells, no ir-cells being found in the brain area. These results suggest that LHRH neurons originate in the olfactory placode and then migrate into the forebrain along the olfactory nerve.
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页码：241 / 244
页数：4
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