FUSIDIC ACID - INHIBITION OF FACTOR T2 IN RETICULOCYTE PROTEIN SYNTHESIS

被引:82
作者
MALKIN, M
LIPMANN, F
机构
[1] Rockefeller University, New York
关键词
D O I
10.1126/science.164.3875.71
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The steroid antibiotic fusidic acid inhibits reticulocyte protein synthesis. This inhibition appears to be due to interference with the activity of the T2 supernatant fraction, and strengthens the proposition that T2 is functionally analogous to the G-factor of bacterial protein synthesis, which is also specifically inhibited by this antibiotic.
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页码:71 / &
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