A STUDY OF URICASE BIOSENSOR BASED ON A GLASSY-CARBON ELECTRODE MODIFIED WITH NAFION AND METHYL VIOLOGEN

被引：16
作者：
JIN, LT
YE, JS
TONG, W
FANG, YZ
机构：
[1] Department of Chemistry, East China Normal University, Shanghai, 200062
来源：
MIKROCHIMICA ACTA | 1993年 / 112卷 / 1-4期
关键词：
URICASE; BIOSENSOR; NAFION-MV MODIFIED ELECTRODE;
D O I：
10.1007/BF01243323
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A uricase biosensor was constructed by using bovine serum albumin and glutaraldehyde as cross linker to immobilize uricase on a glassy carbon electrode modified with Nafion and methyl viologen (MV). A linear response of uric acid in serum was observed in a range of 1.0 . 10(-3) to 5.0 . 10(-6) mol/l and the response time is 25 s. This biosensor has the advantage of high sensitivity, fast response as compared with previous sensors and low interferences.
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页码：71 / 75
页数：5
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