(H+-K+)-ATPASE INHIBITING 2-[(2-PYRIDYLMETHYL)SULFINYL]BENZIMIDAZOLES .3. EVIDENCE FOR THE INVOLVEMENT OF A SULFENIC ACID IN THEIR REACTIONS

被引：0

作者：

KRUGER, U ^{[1
]}

SENNBILFINGER, J ^{[1
]}

STURM, E ^{[1
]}

FIGALA, V ^{[1
]}

KLEMM, K ^{[1
]}

KOHL, B ^{[1
]}

RAINER, G ^{[1
]}

SCHAEFER, H ^{[1
]}

BLAKE, TJ ^{[1
]}

DARKIN, DW ^{[1
]}

IFE, RJ ^{[1
]}

LEACH, CA ^{[1
]}

MITCHELL, RC ^{[1
]}

PEPPER, ES ^{[1
]}

SALTER, CJ ^{[1
]}

VINEY, NJ ^{[1
]}

机构：

[1] SK&F LABS LTD,WELWYN GARDEN CIT L7 1EY,HERTS,ENGLAND

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1990年 / 55卷 / 13期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

页码：4163 / 4168

页数：6

共 7 条

[1] THE PREPARATION OF C-14,S-35 AND C-13 LABELED FORMS OF OMEPRAZOLE [J].

CROWE, AM ;

IFE, RJ ;

MITCHELL, MB ;

SAUNDERS, D .

JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 1986, 23 (01) :21-33

[2] CHEMISTRY OF SULFENIC ACIDS .7. REASON FOR THE HIGH REACTIVITY OF SULFENIC ACIDS - STABILIZATION BY INTRAMOLECULAR HYDROGEN-BONDING AND ELECTRONEGATIVITY EFFECTS [J].

DAVIS, FA ;

JENKINS, LA ;

BILLMERS, RL .

JOURNAL OF ORGANIC CHEMISTRY, 1986, 51 (07) :1033-1040

[3] ACID ACTIVATION OF (H+-K+)-ATPASE INHIBITING 2-(2-PYRIDYLMETHYL-SULPHINYL)BENZIMIDAZOLES - ISOLATION AND CHARACTERIZATION OF THE THIOPHILIC ACTIVE PRINCIPLE AND ITS REACTIONS [J].

FIGALA, V ;

KLEMM, K ;

KOHL, B ;

KRUGER, U ;

RAINER, G ;

SCHAEFER, H ;

SENNBILFINGER, J ;

STURM, E .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1986, (02) :125-127

[4]

Junggren U. K., 1979, Patent No. [EP5129, 5129, EP 5129 A1 19791031]

[5] THE MECHANISM OF ACTION OF THE GASTRIC-ACID SECRETION INHIBITOR OMEPRAZOLE [J].

LINDBERG, P ;

NORDBERG, P ;

ALMINGER, T ;

BRANDSTROM, A ;

WALLMARK, B .

JOURNAL OF MEDICINAL CHEMISTRY, 1986, 29 (08) :1327-1329

[6]

NAGAYA H, 1989, J PHARMACOL EXP THER, V248, P799

[7]

SENNBILFINGER J, 1981, Patent No. 3240248

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