IS THE CYTOSKELETON-PLASMA MEMBRANE COMPLEX INVOLVED IN LENS PROTEIN-BIOSYNTHESIS

被引：17

作者：

BLOEMENDAL, H ^{[1
]}

BENEDETTI, EL ^{[1
]}

RAMAEKERS, FCS ^{[1
]}

DUNIA, I ^{[1
]}

KIBBELAAR, MA ^{[1
]}

VERMORKEN, AJM ^{[1
]}

机构：

[1] UNIV PARIS 7,CNRS,INST RECH BIOL MOLEC,F-75221 PARIS 05,FRANCE

来源：

MOLECULAR BIOLOGY REPORTS | 1979年 / 5卷 / 1-2期

关键词：

D O I：

10.1007/BF00777495

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Calf lens fiber cells contain a population of polyribosomes that direct, at least in vitro, the synthesis of a specific plasma membrane protein MP26. This protein may serve as a marker in terminal differentiation, since it is absent in the lens epithelium but appears in lens fiber plasma membranes. The MP26 manufacturing polyribosomes are found to be associated with a structural complex in which also the cytoskeleton and plasma membranes participate. They can be released from the complex by treatment with DNAse I. This result presumably reflects the involvement of actin in the linkage of the MP26 synthesizing polyribosomes to the cytoskeleton-membrane complex. © 1979 Dr. W. Junk bv Publishers.

引用

页码：99 / 103

页数：5

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