Investigation of anti-inflammatory activity of Aristolochia krisagathra Sivarajan and Pradeep

被引：0

作者：

Paulpriya, Koilpitchai ^{[1
]}

Tresina, Pious Soris ^{[1
]}

Mohan, Veerabahu Ramasamy ^{[1
]}

机构：

[1] VO Chidambaram Coll, Res Dept Bot, Ethnopharmacol Unit, Tuticorin 628008, Tamil Nadu, India

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND ALLIED SCIENCES | 2016年 / 5卷 / 03期

关键词：

Aristolochia krisagathra; paw edema; carrageenan; phytol;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

In the present study, Aristolochia krisagathra whole plant was extracted with ethanol and evaluated for anti-inflammatory activity in rats using a carrageenan induced paw edema method. Ethanol extract exhibited potent anti-inflammatory activity at the dose of 400 mg/kg at 3hr administration (87.19%). The study was compared with standard drug indomethacin 85.11% (10mg/kg). Observed pharmacological activity in the present study provides scientific validation of ethnomedicinal uses of this plant in treating acute inflammation.

引用

页码：132 / 135

页数：4

共 18 条

[1] ROLE OF OXYGEN RADICALS AND ARACHIDONIC-ACID METABOLITES IN THE REVERSE PASSIVE ARTHUS REACTION AND CARRAGEENAN PAW EDEMA IN THE RAT [J].

BOUGHTONSMITH, NK ;

DEAKIN, AM ;

FOLLENFANT, RL ;

WHITTLE, BJR ;

GARLAND, LG .

BRITISH JOURNAL OF PHARMACOLOGY, 1993, 110 (02) :896-902

[2]

Brinda P, 1988, B MED ETHNOBOT RES, V3, P84

[3]

Cathrine L, 2011, INT J CURR PHARM RES, V13, P71

[4] Anti-inflammatory activity of Bacopa monniera in rodents [J].

Channa, S ;

Dar, A ;

Anjum, S ;

Yaqoob, M ;

Atta-ur-Rahman .

JOURNAL OF ETHNOPHARMACOLOGY, 2006, 104 (1-2) :286-289

[5]

Crunkhorn P., 1971, BRIT J PHARMACOL, V42, P96

[6]

Denko CW, 1992, BIOCH INFLAMMATION, P177, DOI 10.1007/978-94-011-2996-1_9

[7]

DIROSA M, 1972, J PHARM PHARMACOL, V24, P89, DOI 10.1111/j.2042-7158.1972.tb08940.x

[8]

Henson P.M., 1989, MEDIATORS INFLAMMATO, P404

[9]

Jegadeeswari P., 2012, Journal of Current Chemical and Pharmaceutical Sciences, V2, P226

[10]

Jegadeeswari P., 2014, INT J PHARMACEUT, V4, P410

← 1 2 →