INFLUENCE OF SIALIC-ACID CONTENT OF MEMBRANES ON THEIR SENSITIVITY TO SILICA AND ALUMINATE-MODIFIED SILICA

被引：12

作者：

DEPASSE, J

机构：

[1] Chimie Générale 1, Faculté des Sciences, Université Libre de Bruxelles, 1050 Brussels, 50, Avenue F. Roosevelt

来源：

ENVIRONMENTAL RESEARCH | 1978年 / 16卷 / 1-3期

关键词：

D O I：

10.1016/0013-9351(78)90145-7

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The hemolytic activities of silica and aluminate-modified silica (AM silica) have been tested. Sheep erythrocytes are equally sensitive to silica and AM silica. Horse erythrocytes are more resistant than sheep erythrocytes, and more senstive to silica than to AM silica. After neuraminidase treatment, the behavior of horse erythrocytes becomes nearly the same as that of sheep erythrocytes. It appears that the sensitivity of the cell to silica or aluminated silica is strongly dependent on the sialic acid content of the membrane. This observation may be related to the strong influence of the aluminum content of silica on its in vivo toxicity. © 1978.

引用

页码：88 / 91

页数：4

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