A Review of Topical Diclofenac Use in Musculoskeletal Disease

被引：36

作者：

Nair, Bindu ^{[1
]}

Taylor-Gjevre, Regina ^{[1
]}

机构：

[1] Univ Saskatchewan, Royal Univ Hosp, Div Rheumatol, Saskatoon, SK S7N 0W8, Canada

来源：

PHARMACEUTICALS | 2010年 / 3卷 / 06期

关键词：

NSAIDs; musculoskeletal; osteoarthritis; diclofenac;

D O I：

10.3390/ph3061892

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly prescribed medications for the treatment of musculoskeletal disorders. Osteoarthritis is the most common form of arthritis in humans and its prevalence rises with age. Oral NSAIDs have potential associated toxicities that must be monitored for and can limit the use of these drugs in certain populations including people of older age. Topical NSAIDs are now being recognized as an option for the treatment strategy of osteoarthritis. We review the efficacy and safety of one of the most common topical NSAIDS, topical diclofenac, for the treatment of osteoarthritis.

引用

页码：1892 / 1908

页数：17

共 63 条

[1]

Altman RD, 2000, ARTHRITIS RHEUM-US, V43, P1905

[2] Diclofenac Sodium Gel in Patients with Primary Hand Osteoarthritis: A Randomized, Double-blind, Placebo-controlled Trial [J].

Altman, Roy D. ;

Dreiser, Renee-Liliane ;

Fisher, Chester L. ;

Chase, Walter F. ;

Dreher, Donatus S. ;

Zacher, Josef .

JOURNAL OF RHEUMATOLOGY, 2009, 36 (09) :1991-1999

[3] INTRAOSSEOUS PHLEBOGRAPHY, INTRAOSSEOUS PRESSURE MEASUREMENTS AND TC-99M POLYPHOSPHATE SCINTIGRAPHY IN PATIENTS WITH VARIOUS PAINFUL CONDITIONS IN THE HIP AND KNEE [J].

ARNOLDI, CC ;

DJURHUUS, JC ;

HEERFORDT, J ;

KARLE, A .

ACTA ORTHOPAEDICA SCANDINAVICA, 1980, 51 (01) :19-28

[4] Treatment of osteoarthritis of the knee with a topical diclofenac solution: a randomised controlled, 6-week trial [ISRCTN53366886] [J].

Baer, PA ;

Thomas, LM ;

Shainhouse, Z .

BMC MUSCULOSKELETAL DISORDERS, 2005, 6 (1)

[5] Randomized Controlled Trial of Diclofenac Sodium Gel in Knee Osteoarthritis [J].

Barthel, H. Richard ;

Haselwood, Douglas ;

Longley, Selden, III ;

Gold, Morris S. ;

Altman, Roy D. .

SEMINARS IN ARTHRITIS AND RHEUMATISM, 2009, 39 (03) :203-212

[6]

BELLAMY N, 1988, J RHEUMATOL, V15, P1833

[7] Bone scintigraphy in chronic knee pain:: comparison with magnetic resonance imaging [J].

Boegård, T ;

Rudling, O ;

Dahlström, J ;

Dirksen, H ;

Petersson, IF ;

Jonsson, K .

ANNALS OF THE RHEUMATIC DISEASES, 1999, 58 (01) :20-26

[8] Effect of a topical diclofenac solution for relieving symptoms of primary osteoarthritis of the knee: a randomized controlled trial [J].

Bookman, AAM ;

Williams, KSA ;

Shainhouse, JZ .

CANADIAN MEDICAL ASSOCIATION JOURNAL, 2004, 171 (04) :333-338

[9] Impact of osteoarthritis on individuals and society: how much disability? Social consequences and health economic implications [J].

Brooks, PM .

CURRENT OPINION IN RHEUMATOLOGY, 2002, 14 (05) :573-577

[10]

Bruhlmann P, 2003, CLIN EXP RHEUMATOL, V21, P193

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