HEPATITIS-C VIRUS IN DIALYSIS UNITS - A MULTICENTER STUDY

被引：28

作者：

DAPORTO, A

ADAMI, A

SUSANNA, F

CALZAVARA, P

POLI, P

CASTELLETTO, MR

AMICI, GP

TEODORI, T

OKOLICSANYI, L

机构：

[1] GEN HOSP,DIALYSIS UNIT,I-31100 TREVISO,ITALY

[2] GEN HOSP TREVISO,CTR BLOOD TRANSFUS,TREVISO,ITALY

[3] UNIV PARMA,CHAIR GASTROENTEROL,I-43100 PARMA,ITALY

[4] GEN HOSP TREVISO,INST MICROBIOL,TREVISO,ITALY

[5] GEN HOSP CONEGLIANO,DIALYSIS UNIT,CONEGLIANO,ITALY

[6] GEN HOSP CASTELFRANCO VENETO,DIALYSIS UNIT,CASTELFRANCO VENE,ITALY

来源：

NEPHRON | 1992年 / 61卷 / 03期

关键词：

HEPATITIS-C VIRUS; HEMODIALYSIS;

D O I：

10.1159/000186916

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Three hundred and eighty-seven chronic hemodialysis patients were evaluated, in a multicenter study, to investigate the epidemiology of hepatitis C virus. In anti-HCV seropositive patients, serum ALT values and blood transfusions were retrospectively compared; blood donors were studied for serum transaminases. In seropositive patients without previous blood transfusions, analysis of dialysis schedule was done. Eventually, the intrafamilial transmission of hepatitis C virus was studied in 104 family members. The prevalence of HCV infection in hemodialysis patients was 15.7%. The incidence of acute hepatitis was frequent, while chronic hepatitis incidence was less than expected (17.5%). Intrafamilial diffusion was low (1.9%). Blood-transfusion-related infections seem to be negligible, while cross-contamination in dialysis units seems to be very important.

引用

页码：309 / 310

页数：2