ONE-STEP SYNTHESIS OF TERTIARY ALPHA-AMINO KETONES AND ALPHA-AMINO ESTERS FROM AMINES AND DIAZOCARBONYL COMPOUNDS

被引：0
作者：
WEST, FG
GLAESKE, KW
NAIDU, BN
机构：
来源：
SYNTHESIS-STUTTGART | 1993年 / 10期
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暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Diazoketones and diazoesters react with tertiary amines in the presence of copper powder to form transient ammonium ylides. These ylides undergo facile [1,2]-shift from N to C (Stevens rearrangement) of the best migrating group. Overall, alpha-substituted alpha-amino ketones or alpha-amino esters are formed in one step from simple reactants.
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页码：977 / 980
页数：4
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