TOTAL SYNTHESIS OF (+/-)-MERIDINOL, (+/-)-EPIMERIDINOL, AND A RELATED CYCLOLIGNAN

被引：4

作者：

AMER, A ^{[1
]}

BAUER, F ^{[1
]}

ZIMMER, H ^{[1
]}

机构：

[1] UNIV CINCINNATI,DEPT CHEM,CINCINNATI,OH 45221

来源：

JOURNAL OF NATURAL PRODUCTS | 1993年 / 56卷 / 04期

关键词：

D O I：

10.1021/np50094a021

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The naturally occurring lignan meridinol [5] was synthesized in a racemic form in a convergent manner involving a Grignard reaction on E-4-(3,4-methylenedioxybenzylidene)-2,3(2H,5H)-furandione [7]. The hitherto unknown epimeridinol [11] and the cyclolignan 15 were also prepared. The structure assignments of the synthesized lignans are determined by their spectroscopic data.

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页码：600 / 605

页数：6

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