LANGERHANS CELLS IN THE IMMUNOPATHOLOGY OF CONTACT ALLERGIC DERMATITIS

被引：0
作者：
LIPOZENCIC, J
LACKOVIC, G
RODE, B
CAJKOVAC, V
机构：
[1] KLIN BOLNICKOG CTR,ZAGREB,CROATIA
[2] PRIRODOSLOVNO MATEMAT FAK SVEUCILISTA,ZOOL ZAVOD,ZAGREB,CROATIA
[3] SESTRE MILOSRDNICE STOMATOLOSKOG FAK SVEUCILISTA,BOLNICE KLIN,ZAGREB,CROATIA
[4] SESTRE MILOSRDNICE STOMATOLOSKOG FAK SVEUCILISTA,ZA KOZNE & SPOLNE BOLESTI KLIN,ZAGREB,CROATIA
来源：
EUROPEAN JOURNAL OF HISTOCHEMISTRY | 1994年 / 38卷 / 04期
关键词：
LANGERHANS CELLS; CONTACT ALLERGIC DERMATITIS; CONTACT SENSITIVITY; ENZYME HISTOCHEMISTRY; IMMUNOHISTOCHEMISTRY;
D O I：
暂无
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The functional morphology, topography and frequency of Langerhans cells (LCs), which are significant factors in the pathogenesis of contact allergic dermatitis (CAD), were studied by histoenzymatic methods (adenosine triphosphatase (ATP-ase), acid phosphatase (AF and alpha naphtylacetate esterase (ANAE), immunohistochemical methods (indirect immunoperoxidase (IPO) with the monoclonal antibody OKT 6), and the peroxidase-antiperoxidase (PAP) method with the polyclonal S-100 antibody in skin biopsies of 24 patients with CAD, as well in skin biopsies in experimental models in guinea pigs. The results confirmed the significant role of LCs in the pathogenesis of contact allergic dermatitis.
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页码：303 / 310
页数：8
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