CONNECTIN, AN ELASTIC PROTEIN OF STRIATED-MUSCLE

被引:111
作者
MARUYAMA, K
机构
[1] Department of Biology, Faculty of Science, Chiba University, Chiba
关键词
CONNECTIN; TITIN; ELASTIC PROTEIN; STRIATED MUSCLE;
D O I
10.1016/0301-4622(94)85021-6
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Connectin, also called titin, a giant elastic protein of striated muscle (approximate to 3000 kDa) mainly consists of fibronectin type III and immunoglobulin C2 globular domains, the beta-sheets of which are parallel to the main axis of the molecule. One connectin molecule runs through the I band and binds onto the myosin filament up to the M line starting from the Z line. It positions the myosin filament at the center of a sarcomere. Connectin is also responsible for resting tension generation. Biodiversity of the connectin family exists in invertebrate muscle.
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页码:73 / 85
页数:13
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