SYNTHESIS OF 3'-AZIDO-5'-HOMOTHYMIDINE ANALOGS

被引：8

作者：

GAUTIER, C ^{[1
]}

LEROY, R ^{[1
]}

MONNERET, C ^{[1
]}

ROGER, P ^{[1
]}

机构：

[1] INST CURIE,BIOL SECT,F-75005 PARIS,FRANCE

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 28期

关键词：

ANTIVIRAL; HOMONUCLEOSIDE;

D O I：

10.1016/S0040-4039(00)92706-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1-(3'-azido-2',3',5'-trideoxy-beta-D-allofuranosyl) thymine 13, and 1-(3'-azido-3',5'-dideoxy-beta-D-(glucofuranosyl) thymine 20 and its 2'-O-methyl ether 22 were synthesized starting from 1,2-O-isopropylidene-alpha-D-glucopyranose and from 1,2-O-isopropylidene-alpha-D-allofuranose, respectively.

引用

页码：3361 / 3364

页数：4

共 8 条

[1] EPIMERIZATION DURING THE ACETOLYSIS OF 3-O-ACETYL-5-O-BENZOYL-1,2-O-ISOPROPYLIDENE-3-C-METHYL-ALPHA-D-RIBOFURANOSE - SYNTHESIS OF 3'-C-METHYLNUCLEOSIDES WITH THE BETA-D-RIBO-CONFIGURATIONS AND ALPHA-D-ARABINO-CONFIGURATIONS [J].