GROWTH FAILURE, SOMATOMEDIN AND GROWTH-HORMONE LEVELS IN JUVENILE DIABETES-MELLITUS - PILOT-STUDY

被引：16

作者：

NASH, H

机构：

[1] Adelaide Children's Hospital, South Australia

来源：

AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE | 1979年 / 9卷 / 03期

关键词：

D O I：

10.1111/j.1445-5994.1979.tb04131.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Summary: Growth hormone (hGH) responsiveness to exercise and Somatomedin C (SmC) activity were measured in ten children with insulin‐deficient diabetes mellitus. Four of the ten children showed a significant degree of growth retardation. Normal SmC activity was found in association with elevated hGH levels. The hypothesis that growth‐retarded diabetics have a failure of Sm production despite high hGH levels (analogous to malnutrition and Laron dwarfism) was not substantiated by this study. Chronic deficiency of insulin, itself a somatomedin, may play a major role in diabetic growth failure. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：245 / 249

页数：5

共 25 条

[1] THE GROWTH OF JUVENILE DIABETICS [J].