REDUCTION OF MITOCHONDRIAL PYRUVATE-DEHYDROGENASE PHOSPHATASE-ACTIVITY IN LACTATING RAT MAMMARY-GLAND FOLLOWING STARVATION OR INSULIN DEPRIVATION

被引：12
作者：
BAXTER, MA
COORE, HG
机构：
来源：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1979年 / 87卷 / 02期
关键词：
D O I：
10.1016/0006-291X(79)91814-X
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The initial rates of activation of inactivated pyruvate dehydrogenase from lactating rat mammary gland and from pig heart were employed to assay pyruvate dehydrogenase phosphatase activity in mammary gland mitochondrial extracts. 24 h-starvation or 3 h-deprivation of insulin diminished phosphatase activity compared to fed controls. Refeeding and insulin treatment of 24 h starved animals restored in 1 h control levels of phosphatase activity. © 1979.
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页码：433 / 440
页数：8
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