Salivary Duct Carcinoma of Parotid Gland

Context: Salivary duct carcinoma accounts for < 1% of the epithelial salivary gland neoplasms of which 75% occur in the parotid gland. Aims: Salivary duct carcinomas are rare and commonly affect the parotid gland followed by the submandibular gland. A case report and a brief review of the salivary duct carcinoma of parotid gland is presented here. Settings and designs: The representative tissue received was 10% formalin fixed, was 8 cm in diameter, and was floated on the surface of the fixative. Materials and methods: Sections of 0.2 mu thickness were obtained from paraffin-embedded tissues that had been processed and stained with routine hematoxylin and eosin stain. These stained sections were then reviewed. Conclusion: Examinations of paraffin-embedded section showed cribriform pattern of tumor cells invading into tissue parenchyma and central comedo necrosis, the typical feature of salivary duct carcinoma.