A CONVENIENT METHOD FOR THE PREPARATION OF (Z)-(2-AMINOTHIAZOL-4-YL)-2-METHOXYIMINOACETYLCHLORIDE HYDROCHLORIDE

被引：3
|
作者：
DALOIA, E [1 ]
LIM, G [1 ]
MELTON, J [1 ]
ROUBIE, J [1 ]
机构：
[1] BRISTOL MYERS SQUIBB CO,DIV BIOCHEM,CHEM DEV LABS,SYRACUSE,NY 13221
来源：
SYNTHETIC COMMUNICATIONS | 1993年 / 23卷 / 18期
关键词：
D O I：
10.1080/00397919308012597
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Successive treatment of (Z) - (2-aminothiazol-4-yl)-2-methoxyiminoacetic acid, 1, with 0.9 to 1.0 equiv. of hydrogen chloride and 1.04 equiv. (chloromethylene)dimethylammonium chloride provides (Z) - (2-aminothiazol-4-yl)-2-methoxyiminoacetyl-chloride hydrochloride, 3, in high yield.
引用
收藏
页码：2617 / 2622
页数：6
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