POSSIBLE ASSOCIATION OF C-HARVEY-RAS-1 (HRAS-1) MARKER WITH AUTISM

被引：49

作者：

HERAULT, J

PERROT, A

BARTHELEMY, C

BUCHLER, M

CHERPI, C

LEBOYER, M

SAUVAGE, D

LELORD, G

MALLET, J

MUH, JP

机构：

[1] CHR UNIV BRETONNEAU,INSERM,U316,UNITE NERVOUS SYST FETUS CHILD,F-37044 TOURS,FRANCE

[2] CNRS,UPR 23,F-91198 GIF SUR YVETTE,FRANCE

来源：

PSYCHIATRY RESEARCH | 1993年 / 46卷 / 03期

关键词：

CHILD PSYCHIATRY; GENETICS; INFANTILE AUTISM; POLYMORPHISM;

D O I：

10.1016/0165-1781(93)90094-W

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

We tested for an association between autism and genes coding for enzymes involved in monoaminergic metabolism and for a linked marker, c-Harvey-Ras-1 (HRAS 1), using restriction fragment length polymorphisms. We did not find evidence of an association between autism and genes coding for tyrosine hydroxylase, dopamine-beta-hydroxylase (DBH), and tryptophan hydroxylase. However, we report a positive association between autism and the locus containing the gene for HRAS-1.

引用

页码：261 / 267

页数：7

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