ENZYMATIC SOLVENT-FREE SYNTHESIS OF SUGAR ACETAL FATTY-ACID ESTERS

被引：87

作者：

FREGAPANE, G ^{[1
]}

SARNEY, DB ^{[1
]}

VULFSON, EN ^{[1
]}

机构：

[1] INST FOOD RES, NORWICH NR4 7UA, NORFOLK, ENGLAND

来源：

ENZYME AND MICROBIAL TECHNOLOGY | 1991年 / 13卷 / 10期

关键词：

SUGAR-FATTY ACID ESTERS; LIPASE; SOLVENT-FREE SYNTHESIS;

D O I：

10.1016/0141-0229(91)90062-F

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

An enzymic solvent-free acylation of sugar acetals with a range of long-chain fatty acids (lauric, myristic, palmitic, stearic) and their methyl esters is described. The lipase-catalysed reaction was carried out at 1:1 and 2:1 molar ratios of fatty acid or methyl ester of fatty acid to sugar acetal to obtain mono- or diesters, respectively. A range of 6 monoesters of 1,2-O-isopropylidene-D-glucofuranose and 1,2:3,4-Di-O-isopropylidene-D-galactopyranose as well as 5-mono- and 3,5-diesters of 1,2-O-isopropylidene-D-xylofuranose were prepared. The synthesis was performed at 75-degrees-C in open vials or under vacuum, to provide an equilibrium shift towards the final products via evaporation of water or methanol produced in the course of the reaction. Typically yields of 50-90% were obtained under optimal conditions.

引用

页码：796 / 800

页数：5

共 11 条

[1]

ADLEHORST K, 1990, SYNTHESIS-STUTTGART, P112

[2] TRIGLYCERIDE INTERESTERIFICATION BY LIPASES .1. COCOA BUTTER EQUIVALENTS FROM A FRACTION OF PALM OIL [J].