ALCOHOLISM AND PANIC DISORDER - IS THE COMORBIDITY MORE THAN COINCIDENCE

被引：118
作者：
GEORGE, DT
NUTT, DJ
DWYER, BA
LINNOILA, M
机构：
[1] COLUMBIA UNIV, MED CTR, NEW YORK, NY 10027 USA
[2] UNIV BRISTOL, RECKITT & COLMAN PSYCHOPHARMACOL UNIT, BRISTOL BS8 1TD, AVON, ENGLAND
来源：
ACTA PSYCHIATRICA SCANDINAVICA | 1990年 / 81卷 / 02期
关键词：
alcoholism; comorbidity; panic disorder;
D O I：
10.1111/j.1600-0447.1990.tb06460.x
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
Studies on alcoholic patients have found a higher than expected prevalence of panic disorder, and suggest a positive correlation between the level of alcohol consumption and severity of anxiety. Conversely, there is an increased prevalence of alcoholism among patients with panic disorder and their blood relatives. A comparison of symptoms, physiological and neurochemical changes known to occur in both alcohol withdrawal and panic disorder reveals a degree of similarity between the 2 conditions. Based on the data, we propose that the chemical and cognitive changes occurring as the result of repeated alcohol withdrawals may kindle and condition coincidence of panic attacks in susceptible individuals. Implications of our postulates for treatment of alcohol withdrawal and panic disorder in alcoholics and for future studies are discussed. Copyright © 1990, Wiley Blackwell. All rights reserved
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页码：97 / 107
页数：11
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