MACROPHAGES AND THE HUMAN-IMMUNODEFICIENCY-VIRUS

被引：166

作者：

MELTZER, MS

SKILLMAN, DR

HOOVER, DL

HANSON, BD

TURPIN, JA

KALTER, DC

GENDELMAN, HE

机构：

[1] HIV Immunopathogenesis Program, Dept Cellular Immunology, Walter Reed Army Institute of Research, Washington

来源：

IMMUNOLOGY TODAY | 1990年 / 11卷 / 06期

关键词：

D O I：

10.1016/0167-5699(90)90086-O

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Mononuclear phagocytes are major participants in human immunodeficiency virus (HIV) disease. These cells function as susceptible targets, persistent reservoirs for virus in tissue and key immunoregulatory elements that control the level of virus replication and the extent of disease. In this review, the second of the series, Monte Meltzer and colleagues review the distinct interactions between HIV and monocytes and between HIV and T cells. Understanding this dualism may more clearly define both the pathogenesis of HIV disease and strategies for therapeutic intervention. © 1990.

引用

页码：217 / 223

页数：7

共 35 条

[1]

BENDER BS, 1988, REV INFECT DIS, V10, P1142

[2]

CAMERON PU, 1987, CLIN EXP IMMUNOL, V68, P465

[3]

CLOUSE KA, 1989, J IMMUNOL, V142, P431

[4] A HUMAN-SERUM MANNOSE-BINDING PROTEIN INHIBITS INVITRO INFECTION BY THE HUMAN IMMUNODEFICIENCY VIRUS [J].

EZEKOWITZ, RAB ;

KUHLMAN, M ;

GROOPMAN, JE ;

BYRN, RA .

JOURNAL OF EXPERIMENTAL MEDICINE, 1989, 169 (01) :185-196

[5]

FRIEDMAN RM, 1984, INTERFERON, V3, P319

[6] THE ROLE OF MONONUCLEAR PHAGOCYTES IN HTLV-III LAV INFECTION [J].

GARTNER, S ;

MARKOVITS, P ;

MARKOVITZ, DM ;

KAPLAN, MH ;

GALLO, RC ;

POPOVIC, M .

SCIENCE, 1986, 233 (4760) :215-219

[7] SLOW, PERSISTENT REPLICATION OF LENTIVIRUSES - ROLE OF TISSUE MACROPHAGES AND MACROPHAGE PRECURSORS IN BONE-MARROW [J].

GENDELMAN, HE ;

NARAYAN, O ;

MOLINEAUX, S ;

CLEMENTS, JE ;

GHOTBI, Z .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (20) :7086-7090

[8] THE MACROPHAGE IN THE PERSISTENCE AND PATHOGENESIS OF HIV INFECTION [J].

GENDELMAN, HE ;

ORENSTEIN, JM ;

BACA, LM ;

WEISER, B ;

BURGER, H ;

KALTER, DC ;

MELTZER, MS .

AIDS, 1989, 3 (08) :475-495

[9] EFFICIENT ISOLATION AND PROPAGATION OF HUMAN IMMUNODEFICIENCY VIRUS ON RECOMBINANT COLONY-STIMULATING FACTOR-1-TREATED MONOCYTES [J].

GENDELMAN, HE ;

ORENSTEIN, JM ;

MARTIN, MA ;

FERRUA, C ;

MITRA, R ;

PHIPPS, T ;

WAHL, LA ;

LANE, HC ;

FAUCI, AS ;

BURKE, DS ;

SKILLMAN, D ;

MELTZER, MS .

JOURNAL OF EXPERIMENTAL MEDICINE, 1988, 167 (04) :1428-1441

[10]

GENDELMAN HE, IN PRESS AIDS

← 1 2 3 4 →