Ga-68-DOTA and analogs: Current status and future perspectives

被引：45

作者：

Kilian, Krzysztof ^{[1
]}

机构：

[1] Univ Warsaw, Heavy Ion Lab, Pasteur 5a, PL-02093 Warsaw, Poland

来源：

REPORTS OF PRACTICAL ONCOLOGY AND RADIOTHERAPY | 2014年 / 19卷

关键词：

Position emission tomography; Ga-68 labeled compounds; Bifunctional chelators; (68)Gallium-DOTA-peptides;

D O I：

10.1016/j.rpor.2014.04.016

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The construction of the Ge-68/Ga-68 generator has increased application of radiopharmaceuticals labeled with this isotope in medicine. Ga-68-PET is widely employed in the management of neuroendocrine tumors but favorable chemistry with tri-and tetraaza-ring molecules has opened wide range of Ga-68 application in other fields of PET imaging. This review covers the radiopharmaceuticals labeled with gallium in molecular imaging and shows perspectiveson the use of gallium-68 as a substitute for technetium-99, fluorine-18 and carbon-11 insome applications. (c) 2014 Greater Poland Cancer Centre. Published by Elsevier Urban & Partner Sp. zo.o. All rights reserved.

引用

页码：S13 / S21

页数：9

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