Community-Acquired Necrotizing Pneumonia Caused by ST72-SCCmec Type IV-Methicillin-Resistant Staphylococcus aureus in Korea

被引：5

作者：

Hwang, Ji-Won ^{[1
]}

Joo, Eun-Jeong ^{[2
]}

Ha, Jung Min ^{[1
]}

Lee, Woojoo ^{[1
]}

Kim, Eun ^{[1
]}

Yune, Sehyo ^{[1
]}

Chung, Doo Ryeon ^{[2
]}

Jeon, Kyeongman ^{[3
]}

机构：

[1] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Med, Seoul, South Korea

[2] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Div Infect Dis,Dept Med, Seoul, South Korea

[3] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Div Pulm & Crit Care Med,Dept Med, 81 Irwon Ro, Seoul 135710, South Korea

来源：

TUBERCULOSIS AND RESPIRATORY DISEASES | 2013年 / 75卷 / 02期

关键词：

Methicillin-Resistant Staphylococcus aureus; Pneumonia; Community-Acquired Infections; Koreaprimarily;

D O I：

10.4046/trd.2013.75.2.75

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Methcillin-resistant Staphylococcus aureus (MRSA) has emerged as an important cause of community-acquired infections, which has been recently designated as community-associated (CA) MRSA. Panton-Valentine leukocidin (PVL)-negative multilocus sequence type 72 (ST72)-staphylococcal cassette chromosome mec (SCCmec) type IV has been reported as the predominat CA-MRSA strain in Korea and is commonly associated with skin and soft tissue infections in addition to healthcare-associated pneumonia. However, community-acquired pneumonia (CAP) for this strain has not yet been reported. We hereby report two cases of CAP caused by PVL-negative ST72-SCCmec type IV strain in patients who had no risk factors for MRSA acquisition. While CA-MRSA infections are not yet prevalent in Korea, our cases suggest that CA-MRSA should be considered in cases of severe CAP, especially for cases associated with necrotizing pneumonia.

引用

页码：75 / 78

页数：4

共 15 条

[1] Multilocus sequence typing for characterization of methicillin-resistant and methicillin-susceptible clones of Staphylococcus aureus [J].

Enright, MC ;

Day, NPJ ;

Davies, CE ;

Peacock, SJ ;

Spratt, BG .

JOURNAL OF CLINICAL MICROBIOLOGY, 2000, 38 (03) :1008-1015

[2] Severe community-onset pneumonia in healthy adults caused by methicillin-resistant Staphylococcus aureus carrying the Panton-Valentine leukocidin genes [J].

Francis, JS ;

Doherty, MC ;

Lopatin, U ;

Johnston, CP ;

Sinha, G ;

Ross, T ;

Cai, M ;

Hansel, NN ;

Perl, T ;

Ticehurst, JR ;

Carroll, K ;

Thomas, DL ;

Nuermberger, E ;

Bartlett, JG .

CLINICAL INFECTIOUS DISEASES, 2005, 40 (01) :100-107

[3] Methicillin-resistant staphylococcus aureus disease in three communities [J].

Fridkin, SK ;

Hageman, JC ;

Morrison, M ;

Sanza, LT ;

Como-Sabetti, K ;

Jernigan, JA ;

Harriman, K ;

Harrison, LH ;

Lynfield, R ;

Farley, MM .

NEW ENGLAND JOURNAL OF MEDICINE, 2005, 352 (14) :1436-1444

[4] Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients [J].

Gillet, Y ;

Issartel, B ;

Vanhems, P ;

Fournet, JC ;

Lina, G ;

Bes, M ;

Vandenesch, F ;

Piémont, Y ;

Brousse, N ;

Floret, D ;

Etienne, J .

LANCET, 2002, 359 (9308) :753-759

[5] Factors predicting mortality in necrotizing community-acquired pneumonia caused by Staphylococcus aureus containing panton-valentine leukocidin [J].

Gillet, Yves ;

Vanhems, Philippe ;

Lina, Gerard ;

Bes, Michele ;

Vandenesh, Franccois ;

Floret, Daniel ;

Etienne, Jerome .

CLINICAL INFECTIOUS DISEASES, 2007, 45 (03) :315-321

[6] Severe community-acquired pneumonia due to Staphylococcus aureus, 2003-04 influenza season [J].

Hageman, Jeffrey C. ;

Uyeki, Timothy M. ;

Francis, John S. ;

Jernigan, Daniel B. ;

Wheeler, J. Gary ;

Bridges, Carolyn B. ;

Barenkamp, Stephen J. ;

Sievert, Dawn M. ;

Srinivasan, Arjun ;

Doherty, Meg C. ;

McDougal, Linda K. ;

Killgore, George E. ;

Lopatin, Uri A. ;

Coffman, Rebecca ;

MacDonald, J. Kathryn ;

McAllister, Sigrid K. ;

Fosheim, Gregory E. ;

Patel, Jean B. ;

McDonald, L. Clifford .

EMERGING INFECTIOUS DISEASES, 2006, 12 (06) :894-899

[7] Emergence of community-acquired meticillin-resistant Staphylococcus aureus strain USA300 as a cause of necrotising community-onset pneumonia [J].

Hidron, Alicia I. ;

Low, Cari E. ;

Honig, Eric G. ;

Blumberg, Henry M. .

LANCET INFECTIOUS DISEASES, 2009, 9 (06) :384-392

[8] Community-associated Panton-Valentine leukocidin-negative meticillin-resistant Staphylococcus aureus clone (ST72-MRSA-IV) causing healthcare-associated pneumonia and surgical site infection in Korea [J].

Joo, E. -J. ;

Chung, D. R. ;

Ha, Y. E. ;

Park, S. Y. ;

Kang, S. -J. ;

Kim, S. H. ;

Kang, C. -I. ;

Peck, K. R. ;

Lee, N. Y. ;

Ko, K. S. ;

Song, J. -H. .

JOURNAL OF HOSPITAL INFECTION, 2012, 81 (03) :149-155

[9] A survey of community-associated methicillin-resistant Staphylococcus aureus in Korea [J].

Kim, Eu Suk ;

Song, Jin Su ;

Lee, Hye Jin ;

Choe, Pyoeng Gyun ;

Park, Kyung Hwa ;

Cho, Jae Hyun ;

Park, Wan Beom ;

Kim, Sung-Han ;

Bang, Ji-Hwan ;

Kim, Dong-Min ;

Park, Kyoung Un ;

Shin, Sue ;

Lee, Mi Suk ;

Choi, Hee Jung ;

Kim, Nam Joong ;

Kim, Eui-Chong ;

Oh, Myoung-don ;

Kim, Hong Bin ;

Choe, Kang Won .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2007, 60 (05) :1108-1114

[10] Involvement of Panton-Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia [J].

Lina, G ;

Piémont, Y ;

Godail-Gamot, F ;

Bes, M ;

Peter, MO ;

Gauduchon, V ;

Vandenesch, F ;

Etienne, J .

CLINICAL INFECTIOUS DISEASES, 1999, 29 (05) :1128-1132

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