NERVE GROWTH-FACTOR IN THE SYNOVIAL-FLUID OF PATIENTS WITH CHRONIC ARTHRITIS

被引：243

作者：

ALOE, L ^{[1
]}

TUVERI, MA ^{[1
]}

CARCASSI, U ^{[1
]}

LEVIMONTALCINI, R ^{[1
]}

机构：

[1] UNIV ROME LA SAPIENZA,CHAIR RHEUMATOL 2,I-00185 ROME,ITALY

来源：

ARTHRITIS AND RHEUMATISM | 1992年 / 35卷 / 03期

关键词：

D O I：

10.1002/art.1780350315

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Cytokines regulate nerve growth factor (NGF) synthesis during inflammatory processes. Since cytokines are also involved in the inflammatory processes of autoimmune rheumatic diseases, we examined levels of NGF in patients with rheumatoid or other types of chronic arthritis. NGF was present in the synovial fluid and synovium of patients with chronic arthritis, but was undetectable in control fluids. We conclude that NGF might be involved in the pathogenesis of arthritis.

引用

页码：351 / 355

页数：5

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