DIRECT ANALYSIS OF KRYPTOFIX 2.2.2 IN 18FDG BY GAS-CHROMATOGRAPHY USING A NITROGEN-SELECTIVE DETECTOR

被引：18
|
作者：
FERRIERI, RA
SCHLYER, DJ
ALEXOFF, DL
FOWLER, JS
WOLF, AP
机构：
[1] Department of Chemistry, Brookhaven National Laboratory, Upton
来源：
NUCLEAR MEDICINE AND BIOLOGY | 1993年 / 20卷 / 03期
关键词：
D O I：
10.1016/0969-8051(93)90061-X
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
A method is described for the direct measurement of Kryptofix 2.2.2 levels in F-18DG preparations dissolved in isotonic saline using gas chromatography coupled with a nitrogen-selective detector. The cryptand can be eluted intact in 2 min time from a short megabore capillary column, and detected at levels as low as 0.25 mug/mL. This method offers rapid, quantitative and sensitive detection of Kryptofix 2.2.2 levels in F-18DG thus making it amenable to routine quality assurance testing.
引用
收藏
页码：367 / 369
页数：3
相关论文
共 50 条
  • [31] DETERMINATION OF AMINO-ACIDS AND AMINES FROM BRAIN PERFUSATES USING GAS-CHROMATOGRAPHY AND NITROGEN-SELECTIVE DETECTION
    WOLFENSBERGER, M
    AMSLER, U
    CANZEC, V
    EXPERIENTIA, 1981, 37 (06): : 617 - 617
  • [32] IMPROVED METHOD FOR THE DETERMINATION OF SUGARS USING CAPILLARY GAS-CHROMATOGRAPHY WITH FLAME-IONIZATION AND NITROGEN-SELECTIVE DETECTION
    BURKE, KJM
    BERRY, MC
    COOKE, M
    ANALYST, 1987, 112 (10) : 1427 - 1431
  • [33] GAS-CHROMATOGRAPHIC DETERMINATION OF NITRILOTRIACETIC ACID USING A NITROGEN-SELECTIVE DETECTOR
    WILLIAMS, DT
    BENOIT, F
    MUZIKA, K
    OGRADY, R
    JOURNAL OF CHROMATOGRAPHY, 1977, 136 (03): : 423 - 427
  • [34] SIMULTANEOUS DETERMINATION OF FENTANYL AND ITS MAJOR METABOLITES AND FENTANYL ANALOGS USING GAS-CHROMATOGRAPHY AND NITROGEN-SELECTIVE DETECTION
    KINTZ, P
    MANGIN, P
    LUGNIER, AA
    CHAUMONT, AJ
    JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS, 1989, 489 (02): : 459 - 461
  • [35] DETERMINATION OF OXPENTIFYLLINE AND 4 METABOLITES IN PLASMA AND URINE BY AUTOMATED CAPILLARY GAS-CHROMATOGRAPHY USING NITROGEN-SELECTIVE DETECTION
    BURROWS, JL
    JOLLEY, KW
    JOURNAL OF CHROMATOGRAPHY, 1985, 344 (NOV): : 187 - 198
  • [36] MEASUREMENT OF MOCLOBAMIDE, A NEW MONOAMINE-OXIDASE INHIBITOR, BY GAS-CHROMATOGRAPHY WITH NITROGEN-SELECTIVE DETECTION
    MAGUIRE, KP
    NORMAN, TR
    DAVIES, BM
    BURROWS, GD
    JOURNAL OF CHROMATOGRAPHY, 1983, 278 (02): : 429 - 433
  • [37] DETERMINATION OF HYDRAZINE IN HYDRALAZINE BY CAPILLARY GAS-CHROMATOGRAPHY WITH NITROGEN-SELECTIVE DETECTION AFTER BENZALDEHYDE DERIVATIZATION
    GYLLENHAAL, O
    GRONBERG, L
    VESSMAN, J
    JOURNAL OF CHROMATOGRAPHY, 1990, 511 : 303 - 315
  • [38] ULTRAMICRO GAS-CHROMATOGRAPHIC ANALYSIS FOR ANTICONVULSANTS, WITH USE OF A NITROGEN-SELECTIVE DETECTOR
    VANDEMARK, FL
    ADAMS, RF
    CLINICAL CHEMISTRY, 1976, 22 (07) : 1062 - 1065
  • [39] Potential of GC-Combustion-MS as a Powerful and Versatile Nitrogen-Selective Detector in Gas Chromatography
    Garcia-Bellido, Javier
    Freije-Carrelo, Laura
    Redondo-Velasco, Montserrat
    Piparo, Marco
    Zoccali, Mariosimone
    Mondello, Luigi
    Moldovan, Mariella
    Bouyssiere, Brice
    Giusti, Pierre
    Encinar, Jorge Ruiz
    ANALYTICAL CHEMISTRY, 2023, 95 (31) : 11761 - 11768
  • [40] HIGHLY SENSITIVE ASSAY OF A BENZODIAZEPINE ANTAGONIST IN PLASMA BY CAPILLARY GAS-CHROMATOGRAPHY WITH NITROGEN-SELECTIVE DETECTION
    ZELL, M
    TIMM, U
    JOURNAL OF CHROMATOGRAPHY, 1986, 382 : 175 - 188
12345