DIRECT ANALYSIS OF KRYPTOFIX 2.2.2 IN 18FDG BY GAS-CHROMATOGRAPHY USING A NITROGEN-SELECTIVE DETECTOR

被引：18

作者：

FERRIERI, RA

SCHLYER, DJ

ALEXOFF, DL

FOWLER, JS

WOLF, AP

机构：

[1] Department of Chemistry, Brookhaven National Laboratory, Upton

来源：

NUCLEAR MEDICINE AND BIOLOGY | 1993年 / 20卷 / 03期

关键词：

D O I：

10.1016/0969-8051(93)90061-X

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

A method is described for the direct measurement of Kryptofix 2.2.2 levels in F-18DG preparations dissolved in isotonic saline using gas chromatography coupled with a nitrogen-selective detector. The cryptand can be eluted intact in 2 min time from a short megabore capillary column, and detected at levels as low as 0.25 mug/mL. This method offers rapid, quantitative and sensitive detection of Kryptofix 2.2.2 levels in F-18DG thus making it amenable to routine quality assurance testing.

引用

页码：367 / 369

页数：3

共 9 条

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