共 21 条
EFFECTS OF ANTIBIOTICS ON NONOPSONIZED ADHERENCE OF STAPHYLOCOCCUS-AUREUS TO HUMAN POLYMORPHONUCLEAR LEUKOCYTES
被引:3
作者:
KOHADA, A
[1
]
MIYAKE, Y
[1
]
SUGAI, M
[1
]
TSURU, H
[1
]
SUGINAKA, H
[1
]
机构:
[1] HIROSHIMA UNIV,SCH DENT,DEPT REMOVAL PROSTHODONT,HIROSHIMA 734,JAPAN
关键词:
ADHERENCE;
POLYMORPHONUCLEAR LEUKOCYTE;
ANTIBIOTICS;
STAPHYLOCOCCUS-AUREUS;
D O I:
10.1159/000238832
中图分类号:
R73 [肿瘤学];
学科分类号:
100214 ;
摘要:
We investigated the effects of several antibiotics on the adherence of Staphylococcus aureus FDA 209P to polymorphonuclear leukocytes. Sublethal concentrations of aminoglycosides enhanced staphylococcal adherence to polymorphonuclear leukocytes, whereas beta-lactams, minocycline, ofloxacin and clindamycin decreased the adherence. Chloramphenicol and rokitamycin had no effect. It is likely that the adherence following antibiotic treatment is related to cell surface hydrophobicity determined by the measurement of the contact angle of 1-bromonaphthalene on a monolayer of staphylococcal cells.
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页码:50 / 56
页数:7
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