SEPARATION OF DRUGS BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY WITH POROUS POLYMER RESINS

被引：26

作者：

MATSUDA, R ^{[1
]}

YAMAMIYA, T ^{[1
]}

TATSUZAWA, M ^{[1
]}

EJIMA, A ^{[1
]}

TAKAI, N ^{[1
]}

机构：

[1] UNIV TOKYO, INST IND SCI, MINATO KU, TOKYO 113, JAPAN

来源：

JOURNAL OF CHROMATOGRAPHY | 1979年 / 173卷 / 01期

关键词：

D O I：

10.1016/S0021-9673(01)80447-7

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The separation of cold drugs and neuroleptics by high-performance liquid chromatography with the porous polymer resin DVB-MCL-O (or 11-30-0), which is a styrene-divinylbenzene-methyl methacrylate copolymer substituted with hydroxymethyl groups, was studied. This copolymer was compared with the commercial porous polymers Hitachi gel 3011, 3011-0 and 3030. A very small theoretical plate height was obtained by using DVB-MCL-O and methanol-ammonia solution (99:1) as the stationary and mobile phases, respectively. This combination was the most suitable for the rapid separation of condensed aromatic ring compounds.

引用

页码：75 / 87

页数：13

共 8 条

[1] HIGH-SPEED LIQUID-SOLID CHROMATOGRAPHY OF PHENOTHIAZINES USING COLUMNS PACKED WITH SPHEROSIL POROUS SILICA BEADS [J].