FORMATION OF C-C BOND IN SOLID-PHASE SYNTHESIS USING THE HECK REACTION

被引：78
|
作者：
HIROSHIGE, M [1 ]
HAUSKE, JR [1 ]
ZHOU, P [1 ]
机构：
[1] ARRIS PHARMACEUT CORP,S SAN FRANCISCO,CA 94080
来源：
TETRAHEDRON LETTERS | 1995年 / 36卷 / 26期
关键词：
D O I：
10.1016/0040-4039(95)00855-7
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The palladium promoted vinylation of aryl iodide bound to a solid support was studied. Under the reaction conditions of water/DMF/Pd(OAc)(2)/PPh(3)/base, the reaction proceeds smoothly and leads to moderate to high yield of product at 37 degrees C after 4-18 hours.
引用
收藏
页码：4567 / 4570
页数：4
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