MUTAGENESIS OF THE HA-RAS ONCOGENE IN MOUSE SKIN TUMORS INDUCED BY POLYCYCLIC AROMATIC-HYDROCARBONS

被引:254
作者
BIZUB, D [1 ]
WOOD, AW [1 ]
SKALKA, AM [1 ]
机构
[1] ROCHE INST MOLEC BIOL,ROCHE RES CTR,DEPT MOLEC ONCOL,NUTLEY,NJ 07110
关键词
D O I
10.1073/pnas.83.16.6048
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
引用
收藏
页码:6048 / 6052
页数:5
相关论文
共 38 条
[1]   MOUSE SKIN CARCINOMAS INDUCED INVIVO BY CHEMICAL CARCINOGENS HAVE A TRANSFORMING HARVEY-RAS ONCOGENE [J].
BALMAIN, A ;
PRAGNELL, IB .
NATURE, 1983, 303 (5912) :72-74
[2]   ACTIVATION OF THE MOUSE CELLULAR HARVEY-RAS GENE IN CHEMICALLY-INDUCED BENIGN SKIN PAPILLOMAS [J].
BALMAIN, A ;
RAMSDEN, M ;
BOWDEN, GT ;
SMITH, J .
NATURE, 1984, 307 (5952) :658-660
[3]   3 DIFFERENT MUTATIONS IN CODON-61 OF THE HUMAN N-RAS GENE DETECTED BY SYNTHETIC OLIGONUCLEOTIDE HYBRIDIZATION [J].
BOS, JL ;
VERLAANDEVRIES, M ;
JANSEN, AM ;
VEENEMAN, GH ;
VANBOOM, JH ;
VANDEREB, AJ .
NUCLEIC ACIDS RESEARCH, 1984, 12 (23) :9155-9163
[4]   BIOLOGICAL AND BIOCHEMICAL-PROPERTIES OF HUMAN RASH GENES MUTATED AT CODON-61 [J].
DER, CJ ;
FINKEL, T ;
COOPER, GM .
CELL, 1986, 44 (01) :167-176
[5]  
DIPPLE A, 1983, CANCER RES, V43, P4132
[6]  
DIPPLE A, 1985, P AM ASSOC CANC RES, V26, P89
[7]  
Dipple A., 1984, CHEM CARCINOGENS, P41
[8]   CARCINOGENIC EPOXIDES OF BENZO[A]PYRENE AND CYCLOPENTA[CD]PYRENE INDUCE BASE SUBSTITUTIONS VIA SPECIFIC TRANSVERSIONS [J].
EISENSTADT, E ;
WARREN, AJ ;
PORTER, J ;
ATKINS, D ;
MILLER, JH .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (06) :1945-1949
[9]   THE P21 SRC GENES OF HARVEY AND KIRSTEN SARCOMA-VIRUSES ORIGINATE FROM DIVERGENT MEMBERS OF A FAMILY OF NORMAL VERTEBRATE GENES [J].
ELLIS, RW ;
DEFEO, D ;
SHIH, TY ;
GONDA, MA ;
YOUNG, HA ;
TSUCHIDA, N ;
LOWY, DR ;
SCOLNICK, EM .
NATURE, 1981, 292 (5823) :506-511
[10]   ANALYSIS OF THE TRANSFORMING POTENTIAL OF THE HUMAN H-RAS GENE BY RANDOM MUTAGENESIS [J].
FASANO, O ;
ALDRICH, T ;
TAMANOI, F ;
TAPAROWSKY, E ;
FURTH, M ;
WIGLER, M .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (13) :4008-4012