C-BIFUNCTIONAL SILACYCLOPENTANES AND GERMACYCLOPENTANES .1. 1-SILACYCLOPENTAN-2,3-DIOLS AND 1-GERMACYCLOPENTAN-2,3-DIOLS AND 1-GERMACYCLOPENTAN-3,4-DIOLS

被引：14
作者：
MANUEL, G
BOUKHERROUB, R
机构：
来源：
JOURNAL OF ORGANOMETALLIC CHEMISTRY | 1993年 / 447卷 / 02期
关键词：
D O I：
10.1016/0022-328X(93)80235-4
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
C-bifunctional sila- and germacyclopentanes have some potential as biologically active drugs. Ten representative 1-sila (and 1-germa) cyclopentane-2,3 and 3,4-diols, cis or trans, were synthesized from the corresponding 1-metallacyclopen-3-enes. The influence of the metal, silicon or germanium, on each step leading to 3 sets of alpha-diols is underlined. The stereochemistry of the alpha-diols and their precursors was established by H-1 and C-13 NMR spectroscopy.
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页码：167 / 175
页数：9
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